SCHEMBL4276583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8374278	0.92	KCNH2 (0.56)	KCNH2CACNA1HCYP2D6CACNA1IHTR1A
	SCHEMBL19112666	0.92	KCNH2 (0.70)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4278212	0.90	CACNA1I (0.56)	KCNH2CACNA1HCYP2D6CACNA1IMEN1
	SCHEMBL4278152	0.87	KCNH2 (0.60)	KCNH2CACNA1HCYP2D6CACNA1IHTR1A
	SCHEMBL4285578	0.87	KCNH2 (0.78)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL19113003	0.87	KCNH2 (0.55)	KCNH2CACNA1HCYP2D6CACNA1IDRD4
	SCHEMBL4279851	0.87	KCNH2 (0.57)	KCNH2CACNA1HCYP2D6CACNA1IDRD2
	SCHEMBL4272178	0.85	CACNA1I (0.77)	KCNH2CACNA1HCYP2D6CACNA1IHTR1A
	SCHEMBL14770232	0.85	KCNH2 (0.58)	KCNH2CACNA1HCYP2D6CACNA1IKMT2A
	SCHEMBL4282360	0.85	CACNA1I (0.52)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.