Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169596 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL2169593 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| Bromide SCHEMBL3383397 | 0.79 | KMT2A (0.49) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL3382950 | 0.76 | KMT2A (0.60) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL3382955 | 0.76 | KMT2A (0.60) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| Bromide SCHEMBL963221 | 0.75 | KMT2A (0.44) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL944233 | 0.67 | KMT2A (0.41) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL944234 | 0.67 | KMT2A (0.41) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL3383161 | 0.67 | KMT2A (0.41) | ALDH1A1KMT2AHSD17B10GAARAB9A | |
| SCHEMBL15135268 | 0.66 | KMT2A (0.38) | ALDH1A1KMT2AHSD17B10GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038266-A2 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Abbott Laboratories (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007140385-A2 | THIAZOLE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2007-12-06 | — | — | WO | disclosed |