Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169593 | 1.00 | KMT2A (0.50) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| Bromide SCHEMBL3383397 | 0.98 | KMT2A (0.49) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| Bromide SCHEMBL963221 | 0.94 | KMT2A (0.44) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| SCHEMBL4276772 | 0.80 | ALDH1A1 (0.49) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| SCHEMBL3382955 | 0.80 | KMT2A (0.60) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| SCHEMBL3382950 | 0.80 | KMT2A (0.60) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| SCHEMBL2484586 | 0.76 | NOTUM (0.37) | — | |
| SCHEMBL966076 | 0.76 | RIPK3 (0.32) | — | |
| SCHEMBL944233 | 0.73 | KMT2A (0.41) | KMT2AALDH1A1HSD17B10GAARAB9A | |
| SCHEMBL944234 | 0.73 | KMT2A (0.41) | KMT2AALDH1A1HSD17B10GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546242-B1 | Cannabinoid receptor ligands | ABBVIE INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2457903-B1 | Cannabinoid receptor ligands | ABBVIE INC (US) | 2016-01-13 | — | — | EP | disclosed |
| EP-2546241-B1 | Cannabinoid receptor ligands | ABBVIE INC (US) | 2015-06-17 | — | — | EP | disclosed |
| US-8846730-B2 | Compounds as cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2546241-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2546242-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2457903-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | disclosed |
| US-20100063022-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063022-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | KMT2A 2337/4885ALDH1A1 1868/4885HSD17B10 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.