SCHEMBL4276913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4278858	0.93	PARP10 (0.64)	KDM4EMAPK1HSD17B10NPC1HPGD
	SCHEMBL34465358	0.93	PARP10 (0.64)	KDM4EMAPK1HSD17B10NPC1HPGD
	SCHEMBL4270566	0.89	SMPD1 (0.73)	KDM4EMAPK1NPC1HPGDRAB9A
	SCHEMBL4280782	0.89	MRGPRX4 (0.74)	KDM4EHSD17B10POLBNPC1HPGD
	SCHEMBL4278415	0.87	NPC1 (0.73)	KDM4EMAPK1NPC1HPGDRAB9A
	SCHEMBL1402177	0.87	MAPK1 (0.84)	MAPK1HSD17B10POLBNPC1RAB9A
	SCHEMBL17037223	0.85	SMPD1 (0.55)	KDM4EMAPK1HSD17B10NPC1HPGD
	SCHEMBL30820546	0.85	SMN1; SMN2 (0.62)	KDM4EHSD17B10POLBNPC1HPGD
	SCHEMBL18660058	0.85	SMN1; SMN2 (0.62)	KDM4EHSD17B10POLBNPC1HPGD
	SCHEMBL4279981	0.85	HSD17B10 (0.61)	KDM4EHSD17B10POLBNPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.