SCHEMBL4280782

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1600077	0.92	MRGPRX4 (0.62)	MRGPRX4POLBMAPTTHRBSMN1; SMN2
	SCHEMBL29556736	0.92	MRGPRX4 (0.62)	MRGPRX4POLBMAPTTHRBSMN1; SMN2
	Hydrochloric Acid SCHEMBL10857748	0.91	MRGPRX4 (0.61)	MRGPRX4POLBMAPTTHRBSMN1; SMN2
	SCHEMBL4276913	0.89	KDM4E (0.65)	MRGPRX4POLBMAPTTHRBCASP6
	SCHEMBL29882038	0.87	TSHR (0.83)	MRGPRX4POLBMAPTTHRBCASP6
	SCHEMBL177424	0.87	TSHR (0.83)	MRGPRX4POLBMAPTTHRBCASP6
	SCHEMBL18660058	0.87	SMN1; SMN2 (0.62)	MRGPRX4POLBMAPTTHRBCASP6
	SCHEMBL30820546	0.87	SMN1; SMN2 (0.62)	MRGPRX4POLBMAPTTHRBCASP6
	SCHEMBL4279981	0.87	HSD17B10 (0.61)	MRGPRX4POLBMAPTTHRBCASP6
	SCHEMBL242563	0.87	MRGPRX4 (0.77)	MRGPRX4POLBTSHRSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.