SCHEMBL4276930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29813517	1.00	PARP1 (0.45)	PARP1SMN1; SMN2POLBKDM4ELMNA
	SCHEMBL4277865	1.00	PARP1 (0.45)	PARP1SMN1; SMN2POLBKDM4ELMNA
	SCHEMBL34465305	0.97	PARP1 (0.47)	PARP1SMN1; SMN2KDM4EMAPTTSHR
	SCHEMBL4274997	0.97	PARP1 (0.47)	PARP1SMN1; SMN2KDM4EMAPTTSHR
	SCHEMBL4271222	0.96	KDM4E (0.39)	PARP1KDM4ELMNAMAPTHSD17B10
	SCHEMBL4274927	0.95	PARP1 (0.47)	PARP1SMN1; SMN2KDM4EMAPTHSD17B10
	SCHEMBL13701427	0.95	PARP1 (0.45)	PARP1SMN1; SMN2KDM4EMAPTHSD17B10
	SCHEMBL4277682	0.93	PARP1 (0.44)	PARP1POLBKDM4ENPSR1PDE4B
	SCHEMBL4280633	0.93	SMN1; SMN2 (0.45)	SMN1; SMN2POLBKDM4ELMNAMAPT
	SCHEMBL4274769	0.92	SMN1; SMN2 (0.39)	PARP1SMN1; SMN2POLBKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.