SCHEMBL4277682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4274997	0.95	PARP1 (0.47)	PARP1KDM4EPDE4BPDE4APDE4C
	SCHEMBL34465305	0.95	PARP1 (0.47)	PARP1KDM4EPDE4BPDE4APDE4C
	SCHEMBL4275005	0.93	KDM4E (0.41)	PARP1KDM4EFPR2LCLAT1PDE4B
	SCHEMBL4277865	0.93	PARP1 (0.45)	PARP1KDM4EPDE4BLIG1CTNNB1
	SCHEMBL4276930	0.93	PARP1 (0.45)	PARP1KDM4EPDE4BLIG1CTNNB1
	SCHEMBL29813517	0.93	PARP1 (0.45)	PARP1KDM4EPDE4BLIG1CTNNB1
	SCHEMBL13701427	0.93	PARP1 (0.45)	PARP1KDM4EPDE4BLIG1CTNNB1
	SCHEMBL4274927	0.93	PARP1 (0.47)	PARP1KDM4EPDE4BPDE4APDE4C
	SCHEMBL13701425	0.92	LCLAT1 (0.40)	KDM4EFPR2LCLAT1PDE4BPDE4A
	SCHEMBL4279400	0.91	SMN1; SMN2 (0.41)	KDM4EFPR2LCLAT1PDE4BPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.