SCHEMBL4276934

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4275757	0.94	KCNH2 (0.55)	MAPTGSK3BPOLBALDH1A1KDM4E
	SCHEMBL4272453	0.93	GSK3B (0.48)	MAPTGSK3BPOLBALDH1A1KDM4E
	SCHEMBL16478288	0.92	GSK3B (0.47)	MAPTGSK3BPOLBALDH1A1KDM4E
	SCHEMBL4273172	0.91	KCNH2 (0.57)	MAPTGSK3BPOLBALDH1A1KDM4E
	SCHEMBL14770047	0.89	GSK3B (0.63)	MAPTGSK3BPOLBALDH1A1KDM4E
	SCHEMBL4279835	0.87	KCNH2 (0.49)	GSK3BKCNH2CACNA1HCYP2D6CACNA1I
	SCHEMBL4273491	0.86	MAPT (0.52)	MAPTGSK3BPOLBALDH1A1KDM4E
	SCHEMBL4276941	0.86	CACNA1I (0.49)	GSK3BKCNH2CACNA1HCYP2D6CACNA1I
	SCHEMBL4284048	0.86	CACNA1I (0.51)	GSK3BKCNH2CACNA1HCYP2D6CACNA1I
	SCHEMBL4276491	0.86	CACNA1I (0.64)	KCNH2CACNA1HCYP2D6CACNA1I

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.