Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 5/20 | 0.58 |
| ▸ | BCHE | P06276 | 12/20 | 0.51 |
| ▸ | ACHE | P22303 | 12/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277179 | 1.00 | ITGAL (0.58) | ITGALBCHEACHEDRD2DRD3 | |
| SCHEMBL13879651 | 0.83 | ITGAL (0.57) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL13879650 | 0.82 | CYP3A4 (0.62) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL4276624 | 0.81 | ITGAL (0.57) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL4276627 | 0.81 | ITGAL (0.57) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL13879663 | 0.81 | ITGAL (0.58) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL13879654 | 0.79 | ITGAL (0.63) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL4280079 | 0.79 | ITGAL (0.55) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL4280090 | 0.79 | ITGAL (0.55) | ITGALDRD2DRD3ITGB2ICAM1 | |
| SCHEMBL13879653 | 0.78 | ITGAL (0.52) | ITGALDRD2DRD3ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | ITGAL 4495/4885BCHE 2442/4885ACHE 2994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.