SCHEMBL4277447

SCHEMBL4277447

C=CCOCCOC(=O)CCC(=O)OCCOCC=C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 4/20 0.45
TP53 P04637 2/20 0.45
HIF1A Q16665 2/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 2/20 0.41
ADRA2A P08913 1/20 0.40
ADRA1A P35348 1/20 0.40
MAPT P10636 2/20 0.39
BLM P54132 1/20 0.39
DGKA P23743 1/20 0.38
PKM P14618 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.35
CYP3A4 P08684 2/20 0.34
THRB P10828 2/20 0.34
CACNA1B Q00975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222246 0.92 TSHR (0.40) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL3224284 0.92 TSHR (0.55) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL3287287 0.91 ALDH1A1 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL13325746 0.91 ALDH1A1 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL13895238 0.88 TSHR (0.40) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL7995024 0.88 TSHR (0.51) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL13895230 0.88 TSHR (0.40) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL28607086 0.87 TSHR (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL28617590 0.87 ALDH1A1 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL28605335 0.87 TSHR (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090306284-A1 Curable Fluorinated Copolymers and Coatings and Processes Thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-12-10 US claimed
EP-1966253-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF Lanxess Deutschland GmbH (DE) 2008-09-10 EP claimed
EP-1820809-A1 Coating of substrates with curable fluorinated copolymers Lanxess Deutschland GmbH (DE) 2007-08-22 EP claimed
WO-2007071323-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2007-06-28 WO claimed
EP-1801133-A1 Curable fluorinated copolymers and coatings and processes thereof Lanxess Deutschland GmbH (DE) 2007-06-27 EP claimed
EP-3807286-B1 DEGRADABLE SILANE HAVING THIO AND AMINO GROUPS, SILICIC ACID POLYCONDENSATES AND HYBRID POLYMERS PRODUCED THEREFROM, USE THEREOF AND METHOD FOR PRODUCING THE SILANES FRAUNHOFER GES FORSCHUNG (DE) 2023-09-06 EP disclosed
CN-110431195-B Antifouling composition 佐敦有限公司 2022-02-08 CN disclosed
CN-110431195-A Antifouling composition JOTUN AS 2019-11-08 CN disclosed
WO-2018134291-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2018-07-26 WO disclosed
EP-1966253-B1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2015-08-12 EP disclosed
US-20130184400-A1 Coating of substrates with curable fluorinated copolymers DAIKIN INDUSTRIES, LTD. (CN) 2013-07-18 US disclosed
US-20090306284-A1 Curable Fluorinated Copolymers and Coatings and Processes Thereof LANXESS DEUTSCHLAND GMBH (DE) 2009-12-10 US disclosed
EP-1966253-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF Lanxess Deutschland GmbH (DE) 2008-09-10 EP disclosed
EP-1820809-A1 Coating of substrates with curable fluorinated copolymers Lanxess Deutschland GmbH (DE) 2007-08-22 EP disclosed
WO-2007071323-A1 CURABLE FLUORINATED COPOLYMERS AND COATINGS AND PROCESSES THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2007-06-28 WO disclosed
EP-1801133-A1 Curable fluorinated copolymers and coatings and processes thereof Lanxess Deutschland GmbH (DE) 2007-06-27 EP disclosed