Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octane SCHEMBL28880960 | 0.87 | PPARD (0.50) | HSD17B10CES2CES1GPR84PPARG | |
| Octane SCHEMBL28958535 | 0.87 | PPARD (0.50) | HSD17B10CES2CES1GPR84PPARG | |
| SCHEMBL4277468 | 0.85 | MAPT (0.44) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL28334558 | 0.79 | HSD17B10 (0.43) | HSD17B10GMNNTP53POLBMAPT | |
| Propionic Acid SCHEMBL29247900 | 0.79 | HSD17B10 (0.59) | HSD17B10GMNNTP53POLBMAPT | |
| Propionic Acid SCHEMBL29247958 | 0.79 | HSD17B10 (0.59) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL28425163 | 0.78 | HSD17B10 (0.46) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL28351985 | 0.78 | HSD17B10 (0.42) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL30672717 | 0.78 | FFAR1 (0.39) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL31262790 | 0.77 | GPR84 (0.62) | HSD17B10GMNNTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8231969-B2 | Asymmetrically functionalized nanoparticles | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-07-31 | — | — | US | disclosed |
| US-20090256116-A1 | Asymmetrically Functionalized NanoParticles | UNIVERSITY OF UTAH | 2009-10-15 | — | — | US | disclosed |