Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | CCKAR | P32238 | 3/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4166330 | 1.00 | CTSL (0.46) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4107821 | 0.90 | CTSL (0.45) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4168150 | 0.90 | CTSL (0.45) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4158311 | 0.90 | SCN9A (0.46) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4276999 | 0.90 | CTSL (0.45) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4166403 | 0.90 | CTSL (0.45) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4162888 | 0.89 | CTSL (0.49) | CTSLCTSSCTSKCCKARCCKBR | |
| SCHEMBL4261984 | 0.89 | CTSL (0.49) | CTSLCTSSCTSKCCKARCCKBR | |
| SCHEMBL4167938 | 0.89 | SCN9A (0.48) | CTSLCTSSCTSKSCN9ACCKAR | |
| SCHEMBL4167534 | 0.89 | CTSL (0.48) | CTSLCTSSCTSKCCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912706-A4 | NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIE (IN) | 2009-05-27 | — | — | EP | disclosed |
| EP-1912706-A2 | NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS | Aurigene Discovery Technologies Limited (IN) | 2008-04-23 | — | — | EP | disclosed |
| WO-2006134613-A2 | NOVEL 5-SUBSTITUTED INDOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV (DPP-IV) INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2006-12-21 | — | — | WO | disclosed |