SCHEMBL4278482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4277665	0.92	KDM4E (0.47)	PPARATSHRKDM4EALDH1A1HSD17B10
	SCHEMBL4282880	0.90	TSHR (0.42)	PPARATSHRKDM4EALDH1A1HSD17B10
	SCHEMBL4270615	0.90	SMPD1 (0.48)	PPARATSHRKDM4EALDH1A1HSD17B10
	SCHEMBL4271285	0.88	KDM4E (0.52)	PPARATSHRKDM4EALDH1A1HSD17B10
	SCHEMBL4271329	0.86	TSHR (0.40)	PPARATSHRKDM4EALDH1A1HSD17B10
	SCHEMBL4274955	0.85	KDM4E (0.41)	TSHRKDM4EALDH1A1HSD17B10MAPT
	SCHEMBL4280745	0.85	PDE4A (0.40)	PPARATSHRKDM4EHSD17B10PPARG
	SCHEMBL17037230	0.84	TSHR (0.41)	PPARATSHRKDM4EALDH1A1HSD17B10
	SCHEMBL19066414	0.83	KDM4E (0.43)	TSHRKDM4EALDH1A1HSD17B10MAPT
	SCHEMBL4271714	0.82	TSHR (0.41)	PPARATSHRKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.