SCHEMBL4277665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4271285	0.96	KDM4E (0.52)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4270615	0.96	SMPD1 (0.48)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4282880	0.93	TSHR (0.42)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4278482	0.92	PPARA (0.41)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4639334	0.89	FFAR1 (0.55)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4280795	0.88	KDM4E (0.54)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4271884	0.86	S1PR1 (0.47)	KDM4EALDH1A1HSD17B10MAPTHPGD
	SCHEMBL4271756	0.84	TSHR (0.48)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4277034	0.83	KDM4E (0.46)	KDM4EALDH1A1TSHRHSD17B10MAPT
	SCHEMBL4270587	0.83	ABCB1 (0.43)	KDM4EALDH1A1TSHRHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.