Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPRF | P10586 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297382 | 0.94 | — | — | |
| Pyridine SCHEMBL2130447 | 0.94 | PSMB5 (0.30) | PSMB5 | |
| Pyridine SCHEMBL29860747 | 0.94 | PSMB5 (0.30) | PSMB5 | |
| SCHEMBL2230761 | 0.89 | — | — | |
| SCHEMBL29800322 | 0.89 | — | — | |
| SCHEMBL29554985 | 0.89 | CRHR1 (0.30) | — | |
| SCHEMBL29835243 | 0.88 | — | — | |
| SCHEMBL15512414 | 0.80 | PSMB5 (0.32) | PSMB5PTPRCPTPRFPTPN1CDC25B | |
| SCHEMBL16266909 | 0.76 | — | — | |
| SCHEMBL18011980 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108399-B | 1, 3-butadiene synthesis | 阿朗新科德国有限责任公司 | 2021-06-08 | — | — | CN | claimed |
| US-20090318647-A1 | Olefin Functionalization By Metathesis Reaction | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-12-24 | — | — | US | claimed |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2024-09-17 | — | — | US | disclosed |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2023-02-16 | — | — | US | disclosed |
| CN-115003649-A | Process for the preparation of perfuming intermediates | 弗门尼舍有限公司 | 2022-09-02 | — | — | CN | disclosed |
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | AMGEN INC. (US) | 2022-04-19 | — | — | US | disclosed |
| US-20210230189-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2021-07-29 | — | — | US | disclosed |
| CN-107108399-B | 1, 3-butadiene synthesis | 阿朗新科德国有限责任公司 | 2021-06-08 | — | — | CN | disclosed |
| US-9884924-B2 | Dual reactive functional groups for resins in tires | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2018-02-06 | — | — | US | disclosed |
| WO-2017147410-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC. (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20170058057-A1 | Dual Reactive Functional Groups for Resins in Tires | EXXONMOBIL CHEMICAL PATENTS INC. | 2017-03-02 | — | — | US | disclosed |
| US-8669330-B2 | Olefin triblock polymers via ring-opening metathesis polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-03-11 | — | — | US | disclosed |
| US-20120245294-A1 | Olefin Triblock Polymers via Ring-Opening Metathesis Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230189-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | MCL1, BCL9, BCL2L1 | PSMB5 455/4885TP53 32/4885MAPT 3153/4885 |
| US-11306107-B2 | Compounds that inhibit MCL-1 protein | MCL1, BCL9, BCL2L1 | PSMB5 455/4885TP53 32/4885MAPT 3153/4885 |
| US-20230052348-A1 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | MCL1, BCL9, BCL2L1 | PSMB5 455/4885TP53 32/4885MAPT 3153/4885 |
| US-12091425-B2 | Compounds that inhibit MCL-1 protein | MCL1, BCL9, BCL2L1 | PSMB5 455/4885TP53 32/4885MAPT 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.