SCHEMBL4278525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4274938	0.99	PDE4B (0.40)	PDE4BHPGDMEN1KMT2AELANE
	SCHEMBL4274963	0.98	PDE4B (0.42)	PDE4BHPGDMEN1KMT2APDE4A
	SCHEMBL4286025	0.96	PDE4B (0.40)	PDE4BPDE4APDE4CPDE4DFPR2
	SCHEMBL4271931	0.91	SYK (0.36)	PDE4BHPGDMEN1KMT2APDE4A
	SCHEMBL4271297	0.90	S1PR1 (0.43)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL13701442	0.89	PDE4B (0.41)	PDE4BPDE4APDE4CPDE4DSYK
	SCHEMBL4270719	0.89	S1PR1 (0.44)	PDE4BPDE4APDE4CPDE4D
	SCHEMBL13701432	0.88	MAPT (0.39)	MEN1KMT2AMAPK1HSD17B10
	SCHEMBL4278348	0.88	SYK (0.36)	PDE4BHPGDMEN1KMT2APDE4A
	SCHEMBL4269872	0.87	SMN1; SMN2 (0.42)	HPGDMEN1KMT2AMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.