SCHEMBL4278348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4271931	0.97	SYK (0.36)	SYKPDE4APDE4BPDE4CPDE4D
	SCHEMBL4286025	0.92	PDE4B (0.40)	PDE4APDE4BPDE4CPDE4DFPR2
	SCHEMBL4278392	0.89	FPR2 (0.41)	PDE4APDE4BPDE4CPDE4DFPR2
	SCHEMBL4273664	0.89	PDE4A (0.38)	PDE4APDE4BPDE4CPDE4DPPARG
	SCHEMBL13701432	0.89	MAPT (0.39)	MEN1KMT2AKDM4EALDH1A1HTT
	SCHEMBL4274938	0.89	PDE4B (0.40)	SYKPDE4APDE4BPDE4CPDE4D
	SCHEMBL4274963	0.89	PDE4B (0.42)	SYKPDE4APDE4BPDE4CPDE4D
	SCHEMBL4275217	0.88	PDE4B (0.39)	PDE4APDE4BPDE4CPDE4DPPARG
	SCHEMBL4278525	0.88	PDE4B (0.39)	SYKPDE4APDE4BPDE4CPDE4D
	SCHEMBL4269872	0.87	SMN1; SMN2 (0.42)	HPGDMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.