⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497027 | 1.00 | MEN1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1164727 | 0.97 | — | — | |
| SCHEMBL695108 | 0.92 | — | — | |
| SCHEMBL10731669 | 0.80 | — | — | |
| SCHEMBL23500676 | 0.78 | — | — | |
| SCHEMBL11263233 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL28813769 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL8043855 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL30805 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL18834318 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2338 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4629984-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BioVentures, LLC (US) | 2025-10-15 | — | — | EP | claimed |
| EP-4585665-A1 | POLISHING AGENT, ADDITIVE SOLUTION FOR POLISHING AGENTS AND POLISHING METHOD | AGC INC. (JP) | 2025-07-16 | — | — | EP | claimed |
| US-20250197676-A1 | POLISHING AGENT, ADDITIVE SOLUTION FOR POLISHING AGENT, AND POLISHING METHOD | AGC Inc. (JP) | 2025-06-19 | — | — | US | claimed |
| CN-119930469-A | Chalcone compound containing alpha, beta-unsaturated hydroxamic acid groups and preparation method and application thereof | 河北医科大学 | 2025-05-06 | — | — | CN | claimed |
| CN-118515623-B | Substituted benzisoxazole compound and application thereof in preparation of antitumor drugs | 河北中医药大学 | 2025-04-25 | — | — | CN | claimed |
| CN-118459418-B | Hydroxamic acid HDAC inhibitor and application thereof in preparation of antitumor drugs | 河北中医药大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119768483-A | Polishing agent, additive liquid for polishing agent, and polishing method | ＡＧＣ株式会社 | 2025-04-04 | — | — | CN | claimed |
| CN-119059982-A | Hydroxamic acid Mer/HDAC double-target inhibitor and preparation method and application thereof | 河北科技大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118791483-A | 1H-pyrazolo [3,4-b ] pyridine derivative and preparation method and application thereof | 郑州大学 | 2024-10-18 | — | — | CN | claimed |
| CN-118724824-A | Mer/HDAC double-target inhibitor and preparation method and application thereof | 河北科技大学 | 2024-10-01 | — | — | CN | claimed |
| WO-2008138918-A1 | MONO-HYDROCHLORIC SALTS OF AN INHIBITOR OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA NV (BE) | 2008-11-20 | — | — | WO | claimed |
| EP-1945606-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2008-07-23 | — | — | EP | claimed |
| WO-2007052938-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-05-10 | — | — | WO | claimed |
| EP-1241164-B1 | PROCESS FOR PREPARATION OF TETRAHYDROPYRANYLOXYAMINES | MITSUBISHI RAYON CO (JP) | 2004-05-06 | — | — | EP | claimed |
| US-20040030160-A1 | Process for preparation of tetrahydropyranyoxyamines | MITSUBISHI RAYON CO., LTD. (JP) | 2004-02-12 | — | — | US | claimed |
| US-6541276-B2 | Nucleophilic reaction of alkoxyamine | VERSICOR, INC. | 2003-04-01 | — | — | US | claimed |
| EP-1241164-A1 | PROCESS FOR PREPARATION OF TETRAHYDROPYRANYLOXYAMINES | Mitsubishi Rayon Co., Ltd. (JP) | 2002-09-18 | — | — | EP | claimed |
| US-20010053555-A1 | METHODS FOR SOLID-PHASE SYNTHESIS OF HYDROXYLAMINE COMPOUNDS AND DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | VERSICOR, INC. | 2001-12-20 | — | — | US | claimed |
| WO-1998018754-A1 | METHODS FOR SOLID-PHASE SYNTHESIS OF HYDROXYLAMINE COMPOUNDS AND DERIVATIVES, AND COMBINATORIAL LIBRARIES THEREOF | VERSICOR, INC. (US) | 1998-05-07 | — | — | WO | claimed |
| US-5543542-A | REACTING PHOSPHONOSULFONATE WITH OXIDIZING AGENT, REACTING PRODUCT WITH HYDROXYLAMINE PROTECTING AGENT, THEN WITH SILYL BROMIDE OR IODIDE | LAWRENCE R MICHAEL (US) | 1996-08-06 | — | — | US | claimed |