Xylose

Xylose

SCHEMBL4279236

O=C[C@H](O)[C@H](O)[C@H](O)CO.c1ccncc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
AKR1B1 P15121 1/20 0.32
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xylose SCHEMBL27609335 1.00 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL27673380 0.95 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL28535794 0.93 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
Xylose SCHEMBL27447125 0.89 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1AKR1B1
Xylose SCHEMBL766387 0.89 LMNA (0.36) LMNAL3MBTL1PDE4ATDP1AKR1B1
Demannose SCHEMBL28159049 0.84 LMNA (0.39) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL23830152 0.82 LMNA (0.46) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL23830153 0.82 LMNA (0.46) LMNAL3MBTL1PDE4ATDP1USP2
Demannose SCHEMBL27784462 0.82 LMNA (0.50) LMNAL3MBTL1PDE4ATDP1USP2
Xylose SCHEMBL18424979 0.82 LMNA (0.48) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098654-A1 Selectable genetic marker for use in pasteurellaceae species BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2009-04-16 US disclosed
US-20040033238-A1 Selectable genetic marker for use in pasteurellaceae species MICHIGAN STATE UNIVERSITY, BOARD OF TRUSTEES OPERATING 2004-02-19 US disclosed
WO-2002038733-A2 A SELECTABLE GENETIC MARKER FOR USE IN PASTEURELLACEAE SPECIES MICHIGAN STATE UNIVERSITY (US) 2002-05-16 WO disclosed