⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775329 | 0.78 | — | — | |
| SCHEMBL17435216 | 0.77 | — | — | |
| SCHEMBL3067298 | 0.77 | CRBN (0.44) | — | |
| Hydrochloric Acid SCHEMBL27590032 | 0.73 | — | — | |
| SCHEMBL2841477 | 0.71 | — | — | |
| SCHEMBL21552067 | 0.71 | CRBN (0.50) | — | |
| SCHEMBL24827100 | 0.70 | CRBN (0.47) | — | |
| SCHEMBL4973748 | 0.70 | CRBN (0.47) | — | |
| SCHEMBL31296913 | 0.70 | CRBN (0.47) | — | |
| Diketopiperazine SCHEMBL66638 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390686-B | Pyrrolidine-2, 4-diketone compound, preparation method thereof and application thereof in preparation of osteoclast differentiation inhibitor | 广西中医药大学 | 2025-05-23 | — | — | CN | claimed |
| CN-119390686-A | Pyrrolidine-2, 4-diketone compound, preparation method thereof and application thereof in preparation of osteoclast differentiation inhibitor | 广西中医药大学 | 2025-02-07 | — | — | CN | claimed |
| CN-115504921-A | C (sp) 3 ) Method for preparing pyrrolidine-2,4-diketone derivative from (E) -H-functionalized initiated 1,5-alkenenitrile | 宁波大学 | 2022-12-23 | — | — | CN | claimed |
| CN-115247000-A | Novel pigment and preparation method thereof | 上海百艳实业有限公司 | 2022-10-28 | — | — | CN | claimed |
| US-20210115087-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIV ROCHESTER (US) | 2021-04-22 | — | — | US | claimed |
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER | 2019-08-08 | — | — | US | claimed |
| EP-3475294-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | The University of Rochester (US) | 2019-05-01 | — | — | EP | claimed |
| EP-3452568-A1 | COMPOSITION | Reckitt Benckiser Vanish B.V. (NL) | 2019-03-13 | — | — | EP | claimed |
| WO-2017223207-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER (US) | 2017-12-28 | — | — | WO | claimed |
| WO-2017191462-A1 | COMPOSITION | RECKITT BENCKISER VANISH B.V. (NL) | 2017-11-09 | — | — | WO | claimed |
| CN-1759095-A | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARM INC (US) | 2006-04-12 | — | — | CN | claimed |
| WO-2005009510-A2 | PENETRATION ENHANCER COMBINATIONS FOR TRANSDERMAL DELIVERY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-02-03 | — | — | WO | claimed |
| US-20040132874-A1 | Stabilizer compositions for halogenated polymers, the use thereof and polymers containing said compositions | BAERLOCHER GMBH (DE) | 2004-07-08 | — | — | US | claimed |
| EP-1366114-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS, THE USE THEREOF AND POLYMERS CONTAINING SAID COMPOSITIONS | Baerlocher GmbH (DE) | 2003-12-03 | — | — | EP | claimed |
| WO-2002068526-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS, THE USE THEREOF AND POLYMERS CONTAINING SAID COMPOSITIONS | BAERLOCHER GMBH (DE) | 2002-09-06 | — | — | WO | claimed |
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | claimed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | claimed |
| EP-0252363-B1 | 4-BENZYLOXY-3-PYRROLIN-2-ONE, PREPARATION AND USE IN THE SYNTHESIS OF 2,4-PYRROLIDINEDIONE | LONZA AG (CH) | 1991-01-02 | — | — | EP | claimed |
| EP-0174136-A1 | Derivatives of dihydro-1H-pyrrolo(1,2-c)imidazol-3,5-dione as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-03-12 | — | — | EP | claimed |
| EP-0088259-A2 | Azolyl-pyrrolidinones, process for their preparation and their use as fungicides | Consortium für elektrochemische Industrie GmbH (DE) | 1983-09-14 | — | — | EP | claimed |