SCHEMBL4279491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4276680	0.89	HPGD (0.53)	MAPTS1PR1HSD17B10HPGDTSHR
	SCHEMBL4273072	0.86	HPGD (0.45)	PTGESMAPTHSD17B10HPGDTSHR
	SCHEMBL4271255	0.86	HPGD (0.40)	PTGESMAPTS1PR1HSD17B10HPGD
	SCHEMBL4275161	0.85	ADRA1D (0.41)	PTGESMAPTHPGDKDM4ERAB9A
	SCHEMBL4273113	0.85	HPGD (0.44)	KCNK3KCNK9MAPTS1PR1HSD17B10
	SCHEMBL4278563	0.85	PDE4A (0.45)	MAPTTP53EPHX2DHODH
	SCHEMBL4271699	0.84	MAPT (0.51)	MAPTS1PR1HSD17B10HPGDTSHR
	SCHEMBL4275015	0.84	HPGD (0.50)	KCNK3KCNK9MAPTHSD17B10HPGD
	SCHEMBL4276051	0.83	LCLAT1 (0.42)	KCNK3KCNK9MAPTHSD17B10HPGD
	SCHEMBL4284281	0.83	LCLAT1 (0.41)	KCNK3KCNK9MAPTS1PR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.