Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 6/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788818 | 0.85 | KDM1A (0.50) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL30664080 | 0.85 | KDM1A (0.50) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL29529186 | 0.85 | KDM1A (0.50) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL30316454 | 0.85 | KDM1A (0.50) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL2147836 | 0.85 | KDM1A (0.50) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL594461 | 0.85 | KDM1A (0.50) | HDAC9HCAR2KDM1AMAOBTSHR | |
| Acetone SCHEMBL3363093 | 0.83 | KDM1A (0.44) | HDAC9KIF11HCAR2KDM1AMAOB | |
| SCHEMBL7395445 | 0.83 | KDM1A (0.48) | HDAC9HCAR2KDM1AMAOBTSHR | |
| SCHEMBL2466990 | 0.76 | KDM4E (0.41) | HDAC9KIF11HCAR2KDM1AMAOB | |
| SCHEMBL6440070 | 0.74 | KDM1A (0.56) | KDM1AMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152027-A1 | 5,7-DIHYDRO-6H-PYRROLO[2,3-D]PYRIMIDIN-6-ONE DERIVATIVES FOR MARK INHIBITION | MERCK & CO., INC. (US) | 2009-12-17 | — | — | WO | disclosed |