Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 6/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216510 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL1002064 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL674106 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL1161605 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL29593884 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL83474 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL163842 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL163841 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL5635861 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 | |
| SCHEMBL29512976 | 0.85 | ANPEP (0.48) | ANPEPKDM1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152027-A1 | 5,7-DIHYDRO-6H-PYRROLO[2,3-D]PYRIMIDIN-6-ONE DERIVATIVES FOR MARK INHIBITION | MERCK & CO., INC. (US) | 2009-12-17 | — | — | WO | disclosed |