SCHEMBL83474

SCHEMBL83474

N[C@H]1c2ccccc2C[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.48
KDM1A O60341 4/20 0.47
HTR2A P28223 1/20 0.45
SIGMAR1 Q99720 2/20 0.43
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29593884 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL29775131 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL1002064 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL163841 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL1161605 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL674106 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL3216510 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL5635861 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL163842 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D
SCHEMBL29777394 1.00 ANPEP (0.48) ANPEPKDM1AHTR2ASIGMAR1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624455-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) 2025-10-01 EP claimed
US-20250276986-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF Kangbaida (Sichuan) Biotechnology Co., Ltd (CN) 2025-09-04 US claimed
US-20230033510-A1 Compounds and Methods for Treatment of Visceral Pain ARENA PHARMACEUTICALS, INC. 2023-02-02 US claimed
EP-3385252-B1 CANNABINOID RECEPTOR MODULATORS ARENA PHARM INC (US) 2022-09-21 EP claimed
US-20220234996-A1 Method for Producing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclo-propylpropanoic Acid and the Crystalline Form Thereof for Use as a Pharmaceutical Ingredient BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-07-28 US claimed
CN-114478630-A Chiral diphosphine skeleton compound, preparation method and application thereof 中国科学院上海有机化学研究所 2022-05-13 CN claimed
CN-109501318-B Special-shaped section bar drawing and pressing process adopting PMI foam sandwich 浙江中科恒泰新材料科技有限公司 2021-07-27 CN claimed
CN-113087640-A Chiral ONO tridentate Schiff base carboxylic acid ligand and preparation method and application thereof 合肥工业大学 2021-07-09 CN claimed
US-20210179541-A1 Method for Producing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclo-propylpropanoic Acid and the Crystalline Form Thereof for Use as a Pharmaceutical Ingredient BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-06-17 US claimed
US-20210060040-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2021-03-04 US claimed
WO-1996036584-A1 PROCESS FOR RESOLVING CHIRAL ACIDS WITH 1-AMINOINDAN-2-OLS SEPRACOR, INC. (US) 1996-11-21 WO claimed
EP-0719247-A1 PROCESS FOR PREPARING CYCLIC CIS-1-AMINO-2-ALKANOLS SEPRACOR, INC. (US) 1996-07-03 EP claimed
US-5516943-A Process for preparing cyclic CIS-1-amino-2-alkanols SEPRACOR, INC. (US) 1996-05-14 US claimed
US-5489710-A AMINATION BY MIXING WITH NITRILE SOLVENT, ACIDIFICATION AND HYDROLYZING WITH WATER MERCK & CO., INC. (US) 1996-02-06 US claimed
WO-1995024375-A1 REGIOSPECIFIC PROCESS TO MAKE CIS-1-AMINO-2-ALKANOL FROM EPOXIDE MERCK & CO., INC. (US) 1995-09-14 WO claimed
WO-1995024374-A1 REGIOSPECIFIC PROCESSES TO MAKE CIS-1-AMINO-2-ALKANOL FROM DIOL OR HALOHYDRIN MERCK & CO., INC. (US) 1995-09-14 WO claimed
US-5449830-A Enzyme inhibitors for protease encoded for HIV MARCK & CO., INC. (US) 1995-09-12 US claimed
EP-0658537-A1 Method of producing cis-1-aminoindan-2-ol ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) 1995-06-21 EP claimed
US-5420353-A Protease inhibitors, AIDS MERCK & CO., INC. (US) 1995-05-30 US claimed
WO-1995007880-A1 PROCESS FOR PREPARING CYCLIC CIS-1-AMINO-2-ALKANOLS SEPRACOR, INC. (US) 1995-03-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220234996-A1 Method for Producing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclo-propylpropanoic Acid and the Crystalline Form Thereof for Use as a Pharmaceutical Ingredient FABP3, PCCA, HMGCR ANPEP 499/4885KDM1A 3518/4885HTR2A 1543/4885
US-20210060040-A1 CANNABINOID RECEPTOR MODULATORS CNR1, CNR2, GPR18 ANPEP 4453/4885KDM1A 2336/4885HTR2A 72/4885
US-20250276986-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF PIN1, DHPS, PPOX ANPEP 760/4885KDM1A 3769/4885HTR2A 3309/4885
US-20210179541-A1 Method for Producing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclo-propylpropanoic Acid and the Crystalline Form Thereof for Use as a Pharmaceutical Ingredient FABP3, PCCA, HMGCR ANPEP 499/4885KDM1A 3518/4885HTR2A 1543/4885
US-20230033510-A1 Compounds and Methods for Treatment of Visceral Pain VIP, FABP2, FABP6 ANPEP 2194/4885KDM1A 1799/4885HTR2A 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.