Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355291 | 1.00 | ALDH1A1 (0.44) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL2226410 | 0.98 | ALDH1A1 (0.46) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL14423955 | 0.98 | ALDH1A1 (0.46) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL290076 | 0.98 | ALDH1A1 (0.46) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL18585528 | 0.97 | ALDH1A1 (0.44) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL1079363 | 0.95 | ALDH1A1 (0.46) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL18585615 | 0.95 | ALDH1A1 (0.46) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL22749152 | 0.92 | ALDH1A1 (0.40) | ALDH1A1PDE4ALMNAUSP2SLCO1B1 | |
| Water SCHEMBL2124480 | 0.92 | ALDH1A1 (0.42) | ALDH1A1PDE4A | |
| Demannose SCHEMBL6062262 | 0.90 | ALDH1A1 (0.38) | ALDH1A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166648-A1 | Compositions and Methods for Crystallizing Antibodies | ABBVIE INC (US) | 2015-06-18 | — | — | US | disclosed |
| US-8753839-B2 | Compositions and methods for crystallizing antibodies | ABBVIE INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20090148513-A1 | Compositions and methods for crystallizing antibodies | ABBVIE INC. | 2009-06-11 | — | — | US | disclosed |