SCHEMBL4281004

SCHEMBL4281004

NC1=CCNC(=O)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6179485 0.68
SCHEMBL18175053 0.67
SCHEMBL6035519 0.65 RAD52 (0.41)
SCHEMBL11001085 0.65
SCHEMBL6197570 0.64 GABRP (0.33)
SCHEMBL1177248 0.59
SCHEMBL907942 0.57
SCHEMBL5597052 0.57
SCHEMBL586833 0.57
SCHEMBL1411120 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061761-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-05-18 EP claimed
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP claimed
EP-0061762-B1 NUCLEOTIDE-BASED SUBSTRATES Baker Instruments Corporation (US) 1988-03-02 EP claimed
US-4529796-A Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity BAKER INSTRUMENTS CORPORATION (US) 1985-07-16 US claimed
US-4378458-A A 3-FURYL PHOSPHATE DERIVATIVE HAVING A NUCLEOTIDE BASE SUBSTITUENT IN THE 2 POSITION BAKER INSTRUMENTS CORPORATION (US) 1983-03-29 US claimed
EP-0061760-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP claimed
EP-0061762-A2 Nucleotide-based substrates Baker Instruments Corporation (US) 1982-10-06 EP claimed
EP-0061761-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP claimed
EP-4735593-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM Oxford Nanopore Technologies PLC (GB) 2026-05-06 EP disclosed
EP-4733400-A1 ANTISENSE OLIGONUCLEOTIDE TARGETING HIC-5 SHOWA Medical University (JP) 2026-04-29 EP disclosed
US-20250361549-A1 DETECTION OF EPIGENETIC CYTOSINE MODIFICATION ROCHE SEQUENCING SOLUTIONS INC (US) 2025-11-27 US disclosed
US-20250313838-A1 NUCLEIC ACID FOR TRANSFECTION AGC Inc. (JP) 2025-10-09 US disclosed
EP-4585684-A1 NUCLEIC ACID FOR TRANSFECTION AGC INC. (JP) 2025-07-16 EP disclosed
EP-4573207-A1 DETECTION OF EPIGENETIC MODIFICATIONS F. Hoffmann-La Roche AG (CH) 2025-06-25 EP disclosed
EP-0061760-B1 A METHOD FOR PREPARING A MONONUCLEOTIDE-3'-PHOSPHODIESTER-BASED SUBSTRATE Baker Instruments Corporation (US) 1988-03-02 EP disclosed
US-4529796-A Method for making chromogenic and/or fluorogenic substrates for use in monitoring catalytic or enzymatic activity BAKER INSTRUMENTS CORPORATION (US) 1985-07-16 US disclosed
US-4378458-A A 3-FURYL PHOSPHATE DERIVATIVE HAVING A NUCLEOTIDE BASE SUBSTITUENT IN THE 2 POSITION BAKER INSTRUMENTS CORPORATION (US) 1983-03-29 US disclosed
EP-0061762-A2 Nucleotide-based substrates Baker Instruments Corporation (US) 1982-10-06 EP disclosed
EP-0061761-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP disclosed
EP-0061760-A1 A method for preparing a mononucleotide-3'-phosphodiester-based substrate Baker Instruments Corporation (US) 1982-10-06 EP disclosed