Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008196 | 0.91 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2IGF1RPOLB | |
| SCHEMBL13858849 | 0.88 | ALDH1A1 (0.74) | ALDH1A1KDM4ESMN1; SMN2IGF1RPOLB | |
| SCHEMBL3138383 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2IGF1RTDP1 | |
| SCHEMBL1949645 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2POLBTSHR | |
| SCHEMBL3788224 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4ESMN1; SMN2POLBTSHR | |
| Protocatechualdehyde SCHEMBL5782828 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2POLBTDP1 | |
| SCHEMBL16295256 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2POLBTDP1 | |
| SCHEMBL1949360 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2POLBTDP1 | |
| SCHEMBL13850149 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2POLBHPGD | |
| SCHEMBL15323873 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2IGF1RTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118169-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-7314888-B1 | Compounds and medicinal use thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| EP-1127869-A1 | NOVEL COMPOUNDS AND MEDICINAL USE THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118169-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | SP1, AP1G1, AP1M1 | ALDH1A1 2031/4885KDM4E 3794/4885SMN1; SMN2 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.