Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176571 | 0.87 | BRD4 (0.58) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL5843850 | 0.82 | BRD4 (0.63) | BRD4KMT2AMEN1PTGER1PTGER4 | |
| SCHEMBL8924076 | 0.80 | BRD4 (1.00) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL3175163 | 0.79 | BRD4 (0.63) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL1142084 | 0.78 | BRD4 (0.78) | BRD4KMT2AMEN1PTGER1CYP19A1 | |
| SCHEMBL1137447 | 0.75 | CYP19A1 (0.59) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL13192251 | 0.74 | BRD4 (0.76) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL8121518 | 0.73 | MAPK1 (0.54) | BRD4KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL2892419 | 0.73 | BRD4 (0.58) | BRD4KMT2AMEN1CYP19A1PPIA | |
| SCHEMBL6948195 | 0.72 | BRD4 (0.74) | BRD4KMT2AMEN1CYP19A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |