Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 10/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4294352 | 0.87 | SCNN1A (0.48) | SCNN1A | |
| SCHEMBL4146570 | 0.82 | SCNN1A (0.51) | SCNN1A | |
| SCHEMBL2292130 | 0.81 | SCNN1A (0.51) | SCNN1A | |
| SCHEMBL4875004 | 0.80 | SCNN1A (0.44) | SCNN1A | |
| SCHEMBL2292133 | 0.80 | SCNN1A (0.49) | SCNN1A | |
| Hydrochloric Acid SCHEMBL2382462 | 0.80 | SCNN1A (0.42) | SCNN1A | |
| SCHEMBL6013447 | 0.80 | SCNN1A (0.49) | SCNN1A | |
| Hydrochloric Acid SCHEMBL6013446 | 0.79 | SCNN1A (0.49) | SCNN1A | |
| SCHEMBL6013439 | 0.79 | SCNN1A (0.50) | SCNN1A | |
| Hydrochloric Acid SCHEMBL5673038 | 0.79 | SCNN1A (0.50) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324724-A1 | SOLUBLE AMIDE & ESTER PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324724-A1 | SOLUBLE AMIDE & ESTER PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS | SCN2A, CACNA1B, HCN4 | SCNN1A 13/4885HRH3 1314/4885TLR7 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.