SCHEMBL6013439

SCHEMBL6013439

N=C(N)N(CCCCc1ccc(OCC(=O)N(CCO)CCO)cc1)C(=O)c1nc(Cl)c(N)nc1N

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 17/20 0.50
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6013447 0.90 SCNN1A (0.49) SCNN1A
Hydrochloric Acid SCHEMBL6013446 0.90 SCNN1A (0.49) SCNN1A
SCHEMBL6013452 0.89 SCNN1A (0.48) SCNN1A
SCHEMBL4146570 0.85 SCNN1A (0.51) SCNN1A
SCHEMBL6013451 0.84 SCNN1A (0.51) SCNN1A
SCHEMBL6013444 0.84 SCNN1A (0.46) SCNN1A
Hydrochloric Acid SCHEMBL4294352 0.84 SCNN1A (0.48) SCNN1A
SCHEMBL4686551 0.83 SCNN1A (0.50) SCNN1A
SCHEMBL15092694 0.82 SCNN1A (0.47) SCNN1A
Hydrochloric Acid SCHEMBL5673038 0.82 SCNN1A (0.50) SCNN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656096-A2 METHODS OF REDUCING RISK OF INFECTION FROM PATHOGENS Parion Sciences, Inc. (US) 2006-05-17 EP disclosed
US-20050090505-A1 Methods of reducing risk of infection from pathogens JOHNSON MICHAEL R (US) 2005-04-28 US disclosed
WO-2005034847-A2 METHODS OF REDUCING RISK OF INFECTION FROM PATHOGENS PARION SCIENCES, INC. (US) 2005-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090505-A1 Methods of reducing risk of infection from pathogens KCNN3, KCNN1, KCNN2 SCNN1A 14/4885POLB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.