SCHEMBL4281916

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4285091	0.89	FOS (0.61)	FOSJUNMAPTHIF1AALDH1A1
	SCHEMBL4277088	0.83	FOS (0.48)	FOSJUNMAPTHIF1AALDH1A1
	SCHEMBL4286598	0.79	AKR1C3 (0.41)	FOSJUNMAPTALDH1A1RXRA
	SCHEMBL4286603	0.79	AKR1C3 (0.41)	FOSJUNMAPTALDH1A1RXRA
	SCHEMBL4283756	0.77	FOS (0.60)	FOSJUNMAPTHIF1AALDH1A1
	SCHEMBL4284099	0.77	FOS (0.48)	FOSJUNHSD17B10MAPTHIF1A
	SCHEMBL4279716	0.77	FOS (0.63)	FOSJUNHSD17B10MAPTHIF1A
	SCHEMBL4421331	0.74	FOS (0.56)	FOSJUNMAPTACACB
	SCHEMBL4278052	0.73	FOS (0.55)	FOSJUNMAPTACACBGPR88
	SCHEMBL4283810	0.72	FOS (0.54)	FOSJUNMAPTACACBGPR88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.