⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373292 | 0.93 | SPHK2 (0.41) | — | |
| SCHEMBL9252230 | 0.91 | SPHK2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL28273045 | 0.90 | SPHK1 (0.43) | — | |
| SCHEMBL2494175 | 0.86 | — | — | |
| SCHEMBL245695 | 0.78 | — | — | |
| SCHEMBL8006098 | 0.77 | — | — | |
| SCHEMBL5765981 | 0.73 | FAAH (0.49) | — | |
| SCHEMBL15778751 | 0.71 | — | — | |
| SCHEMBL1415923 | 0.71 | FAAH (0.48) | — | |
| SCHEMBL11802684 | 0.71 | FAAH (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031743-A1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2015-01-29 | — | — | US | disclosed |
| US-8772255-B2 | Cell transfecting formulations of small interfering RNA related compositions and methods of making and use | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| EP-1709195-B1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2014-01-22 | — | — | EP | disclosed |
| US-20090143322-A1 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | CHIRON CORPORATION (US) | 2009-06-04 | — | — | US | disclosed |
| US-7214384-B2 | Lipid-conjugated polyamide compounds | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2007-05-08 | — | — | US | disclosed |
| EP-1709195-A2 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | CHIRON CORPORATION (US) | 2006-10-11 | — | — | EP | disclosed |
| US-20060019912-A1 | Cell transfecting formulations of small interfering RNA related compositions and methods of making and use | CHIRON CORPORATION | 2006-01-26 | — | — | US | disclosed |
| US-6982092-B2 | Method of complexing a nucleic acid with a lipid-conjugated polyamide | CHIRON CORPORATION (US) | 2006-01-03 | — | — | US | disclosed |
| US-20050181988-A1 | Echinocandin cyclic peptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| WO-2005060697-A2 | CELL TRANSFECTING FORMULATIONS OF SMALL INTERFERING RNA, RELATED COMPOSITIONS AND METHODS OF MAKING AND USE | CHIRON CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |
| US-5264457-A | Phenyl amidines sulfonamides useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993016038-A1 | PHENYL AMIDINES SULFONAMIDES USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-08-19 | — | — | WO | disclosed |
| WO-1993014113-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993012103-A1 | PHENYL AMIDINES LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |
| WO-1993012074-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |
| US-5220050-A | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G. D. SEARLE & CO. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1992020705-A1 | PEPTIDE MIMETIC COMPOUNDS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513810-A1 | Peptide mimetic compounds useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992015607-A2 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |
| EP-0502536-A1 | Phenyl amidines derivatives useful as platelet aggregation inhibitors | G.D. Searle & Co. (US) | 1992-09-09 | — | — | EP | disclosed |