SCHEMBL4282547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4275358	0.97	KCNH2 (0.56)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL4274779	0.90	KCNH2 (0.59)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL13569821	0.90	CACNA1I (0.47)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL14770254	0.90	KCNH2 (0.58)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL4277277	0.86	CACNA1I (0.63)	KCNH2CACNA1ICACNA1HCACNA1GCYP2D6
	SCHEMBL4269991	0.86	CACNA1I (0.60)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL4271032	0.85	KCNH2 (0.59)	KCNH2CACNA1ICACNA1HCACNA1GCYP2D6
	SCHEMBL4270371	0.85	KCNH2 (0.61)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL4275219	0.85	KCNH2 (0.59)	KCNH2CACNA1ICACNA1HCACNA1GMCHR1
	SCHEMBL4280515	0.85	CACNA1I (0.61)	KCNH2CACNA1ICACNA1HCACNA1GCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.