Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162511 | 0.82 | DAGLA (0.59) | FAAHDAGLATRPA1CES1 | |
| SCHEMBL2163384 | 0.78 | FAAH (0.53) | FAAHDAGLATRPA1CES1 | |
| SCHEMBL2163273 | 0.78 | DAGLA (0.55) | FAAHDAGLATRPA1CES1 | |
| SCHEMBL2162797 | 0.78 | DAGLA (0.55) | FAAHDAGLATRPA1CES1 | |
| SCHEMBL2162419 | 0.78 | FAAH (0.53) | FAAHDAGLATRPA1 | |
| SCHEMBL2162406 | 0.77 | DAGLA (0.57) | FAAHDAGLACES1 | |
| SCHEMBL2164108 | 0.77 | DAGLA (0.61) | FAAHDAGLACES1 | |
| SCHEMBL2162446 | 0.75 | FAAH (0.60) | FAAHDAGLACES1 | |
| SCHEMBL2163263 | 0.75 | FAAH (0.50) | FAAHDAGLATRPA1 | |
| SCHEMBL2164090 | 0.75 | FAAH (0.53) | FAAHDAGLACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154785-A2 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-23 | — | — | WO | disclosed |