Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12402997 | 0.78 | AHR (0.47) | AHRMAPK1 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL29367365 | 0.65 | AHR (1.00) | AHRMAPK1 | |
| SCHEMBL29441520 | 0.65 | AHR (0.39) | AHRMAPK1 | |
| SCHEMBL26724 | 0.65 | AHR (0.39) | AHRMAPK1 | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 | 0.65 | AHR (1.00) | AHRMAPK1 | |
| SCHEMBL31254111 | 0.65 | AHR (0.39) | AHRMAPK1 | |
| Water SCHEMBL22361230 | 0.62 | AHR (0.37) | AHR | |
| SCHEMBL15724537 | 0.62 | GAA (0.48) | MAPK1 | |
| SCHEMBL29281387 | 0.62 | APEX1 (0.35) | MAPK1 | |
| SCHEMBL28868561 | 0.62 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | CELL THERAPEUTICS, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-7419984-B2 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20040204386-A1 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204386-A1 | Pyrimidines and uses thereof | LPCAT3, LPCAT1, APRT | AHR 2206/4885MAPK1 3470/4885 |
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | LPCAT3, LPCAT1, APRT | AHR 2086/4885MAPK1 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.