2,2',4,4',5,5'-Hexachlorobiphenyl

2,2',4,4',5,5'-Hexachlorobiphenyl

SCHEMBL29367365

Clc1cc(Cl)c(-c2cc(Cl)c(Cl)cc2Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 1.00
MAPK1 P28482 1/20 1.00
TSHR P16473 4/20 0.44
HSD17B10 Q99714 3/20 0.44
HPGD P15428 2/20 0.44
CYP3A4 P08684 2/20 0.44
FLT1 P17948 1/20 0.39
CASP1 P29466 1/20 0.37
TP53 P04637 1/20 0.37
CES1 P23141 1/20 0.36
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 1.00 AHR (1.00) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL4452334 0.82 AHR (0.67) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL9732416 0.82 AHR (0.67) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL29366112 0.82 AHR (0.67) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL6861156 0.82 HSD17B10 (0.78) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL9731778 0.82 HSD17B10 (0.68) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL7085831 0.82 AHR (0.67) AHRMAPK1TSHRHSD17B10HPGD
SCHEMBL348913 0.82 AHR (0.67) AHRMAPK1TSHRHSD17B10HPGD
Polychlorinated Biphenyl 99 SCHEMBL4446838 0.80 AHR (0.63) AHRMAPK1TSHRHSD17B10CYP3A4
SCHEMBL811509 0.80 AHR (0.63) AHRMAPK1TSHRHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025432-A HCBP6 monoclonal antibody and application thereof 爱威科技股份有限公司 2025-05-23 CN claimed
CN-120028549-A Kit for detecting hepatitis C virus core protein binding protein 6 and application thereof 爱威科技股份有限公司 2025-05-23 CN claimed
US-20250051430-A1 NEUTRALIZATION OF ACYL-COA BINDING PROTEIN CONFERS AUTOPHAGY-DEPENDENT ORGAN PROTECTION Institut National de la Santé et de la Recherche Médicale (FR) 2025-02-13 US claimed
CN-119375378-A Analysis and identification method for semi-volatile organic compounds in human serum sample 华中科技大学 2025-01-28 CN claimed
EP-4475883-A1 NEUTRALIZATION OF ACYL-COA BINDING PROTEIN CONFERS AUTOPHAGY-DEPENDENT ORGAN PROTECTION Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2024-12-18 EP claimed
CN-118922206-A Neutralization of acetyl-CoA binding proteins confers autophagy-dependent organ protection 国家医疗保健研究所 2024-11-08 CN claimed
CN-115524428-B Method for measuring indicative polychlorinated biphenyl in food 江苏微谱检测技术有限公司 2024-08-27 CN claimed
CN-117571845-A Method for rapidly and efficiently detecting organic chlorine and polychlorinated biphenyl in soil simultaneously 济南市环境研究院(济南市黄河流域生态保护促进中心) 2024-02-20 CN claimed
CN-116893235-A Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) 2023-10-17 CN claimed
WO-2023152637-A1 NEUTRALIZATION OF ACYL-COA BINDING PROTEIN CONFERS AUTOPHAGY-DEPENDENT ORGAN PROTECTION INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-08-17 WO claimed
CN-113495108-B Method for simultaneously detecting 63 persistent organic pollutants in soil 生态环境部华南环境科学研究所 2023-07-28 CN claimed
CN-115524428-A Method for measuring indicative polychlorinated biphenyl in food 江苏微谱检测技术有限公司 2022-12-27 CN claimed
CN-113311083-B Method for determining seven indicative polychlorinated biphenyls in fish scales 广东产品质量监督检验研究院(国家质量技术监督局广州电气安全检验所、广东省试验认证研究院、华安实验室) 2022-12-16 CN claimed
US-20220351865-A1 METHODS OF BIOLOGICAL AGE EVALUATION AND SYSTEMS USING SUCH METHODS GERO PTE. LTD. (SG) 2022-11-03 US claimed
CN-115166101-A Comprehensive screening method for comprehensively identifying new pollutants in water sample 南京理工大学 2022-10-11 CN claimed
CN-111665313-B Method for determining polychlorinated biphenyl compounds in aquatic products 孟祥龙 2022-10-11 CN claimed
CN-114394680-A Application of microbial agent in degradation of various halogenated organic pollutants 河南科技大学 2022-04-26 CN claimed
CN-120025432-B HCBP6 monoclonal antibody and application thereof 爱威科技股份有限公司 2026-04-21 CN disclosed
CN-109868243-B Microbial agent for accelerating soil organic matter pollution remediation, preparation method and application thereof 中国环境科学研究院 2022-02-01 CN disclosed
CN-109762776-B Microbial agent for improving soil quality, preparation method and application 中国环境科学研究院 2022-02-01 CN disclosed