SCHEMBL4282909

SCHEMBL4282909

O=C(Cl)S(=O)(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518900 0.96
SCHEMBL11293193 0.76
SCHEMBL3417754 0.73 CA5A (0.31)
SCHEMBL31506896 0.73
SCHEMBL21646117 0.73
SCHEMBL9400119 0.73 CA5A (0.31)
SCHEMBL2046056 0.73
SCHEMBL11129190 0.72
SCHEMBL3620813 0.70
SCHEMBL5155872 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034088-A1 SULFOPROPANOIC ACID DERIVATIVES FOR TREATING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2026-02-05 US disclosed
EP-4296670-B1 SULFOPROPANOIC ACID DERIVATIVES FOR TREATING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2025-11-26 EP disclosed
US-12285400-B2 Sulfopropanoic acid derivatives for treating neurodegenerative disorders ALZHEON, INC. (US) 2025-04-29 US disclosed
CN-114206884-B Thienopyrimidine derivatives as ACC inhibitors and use thereof 吉利德科学公司 2024-07-12 CN disclosed
CN-117865911-A Preparation method of 3-methyl-1, 2, 4-thiadiazole-5-carbohydrazide 成都科圣原医药科技有限公司 2024-04-12 CN disclosed
EP-4296670-A2 SULFOPROPANOIC ACID DERIVATIVES FOR TREATING NEURODEGENERATIVE DISORDERS Alzheon, Inc. (US) 2023-12-27 EP disclosed
EP-3829568-B1 SULFOPROPANOIC ACID DERIVATIVES FOR TREATING NEURODEGENERATIVE DISORDERS ALZHEON INC (US) 2023-09-06 EP disclosed
CN-113248481-B EZH2 covalent irreversible inhibitor, preparation method and application thereof 中山大学 2023-03-24 CN disclosed
CN-111212838-B Deuterated Finanentane 欧歌达有限公司 2022-12-02 CN disclosed
US-20220087967-A1 SULFOPROPANOIC ACID DERIVATIVES FOR TREATING NEURODEGENERATIVE DISORDERS ALZHEON, INC. 2022-03-24 US disclosed
US-20070105864-A1 Methods for inhibiting protein kinases SCHERING CORPORATION 2007-05-10 US disclosed
US-20060106023-A1 Novel imidazopyrazines as cyclin dependent kinase inhibitors SCHERING CORPORATION 2006-05-18 US disclosed
US-5264586-A Antibiotics, antitumor, chemical intermediates THE SCRIPPS RESEARCH INSTITUTE (US) 1993-11-23 US disclosed
WO-1993010086-A1 PROCESS FOR PREPARING N-(ARYLSULPHONYL)-CARBAMIDE ACID DERIVATES AND INTERMEDIATES USEFUL FOR CARRYING OUT THIS PROCESS MTA Központi Kémiai Kutató Intézete (HU) 1993-05-27 WO disclosed
WO-1993001810-A1 ANALOGS OF CALICHEAMICIN η1I, METHOD OF MAKING AND USING THE SAME THE SCRIPPS RESEARCH INSTITUTE (US) 1993-02-04 WO disclosed
EP-0279239-B1 MICROBICIDES CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed
US-5135927-A 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid CIBA-GEIGY CORPORATION (US) 1992-08-04 US disclosed
US-4992434-A Prevention of infestation of plants by phytopathogenic microorganisms CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0279239-A1 Microbicides CIBA-GEIGY AG (CH) 1988-08-24 EP disclosed
US-4261728-A PREEMERGENT ACTIVITY MONSANTO COMPANY (US) 1981-04-14 US disclosed