Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12168809 | 0.87 | NR1H4 (0.74) | NR1H4FABP1 | |
| SCHEMBL29904895 | 0.87 | NR1H4 (0.74) | NR1H4FABP1 | |
| SCHEMBL1164481 | 0.87 | NR1H4 (0.64) | NR1H4 | |
| SCHEMBL12168805 | 0.87 | NR1H4 (0.74) | NR1H4FABP1 | |
| SCHEMBL12168807 | 0.86 | NR1H4 (0.66) | NR1H4FABP1 | |
| SCHEMBL20419411 | 0.86 | NR1H4 (0.64) | NR1H4 | |
| SCHEMBL19629742 | 0.86 | NR1H4 (0.64) | NR1H4 | |
| SCHEMBL29904900 | 0.86 | NR1H4 (0.64) | NR1H4 | |
| SCHEMBL4283066 | 0.85 | NR1H4 (0.56) | NR1H4FABP1 | |
| SCHEMBL4278604 | 0.85 | NR1H4 (0.64) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149795-A2 | HETEROCYCLIC CYCLOPROPYL-SUBSTITUTED FXR BINDING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2009-12-17 | — | — | WO | disclosed |
| EP-2128158-A1 | Heterocyclic cyclopropyl-substituted FXR binding compounds | Phenex Pharmaceuticals AG (DE) | 2009-12-02 | — | — | EP | disclosed |