Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743103 | 1.00 | PPARD (0.53) | PPARDALDH1A1GPR84PPARGPPARA | |
| Ethyl Hydrogen Hexylphosphonate SCHEMBL27887144 | 0.95 | GPR84 (0.59) | PPARDALDH1A1GPR84PPARGPPARA | |
| SCHEMBL1487740 | 0.92 | PPARD (0.57) | PPARDALDH1A1GPR84PPARGPPARA | |
| SCHEMBL7570595 | 0.86 | PPARD (0.59) | PPARDTSHRTDP1CETP | |
| SCHEMBL4229202 | 0.85 | PPARD (0.50) | PPARDALDH1A1GPR84PPARGPPARA | |
| SCHEMBL31494109 | 0.85 | PPARD (0.50) | PPARDALDH1A1GPR84PPARGPPARA | |
| SCHEMBL21805452 | 0.85 | PPARD (0.50) | PPARDALDH1A1GPR84PPARGPPARA | |
| Ethyl Hydrogen Hexylphosphonate SCHEMBL27477215 | 0.83 | CETP (0.57) | PPARDALDH1A1GPR84TSHRSLC22A6 | |
| SCHEMBL194845 | 0.82 | PPARD (0.52) | PPARDALDH1A1GPR84PPARGPPARA | |
| Ethyl Hydrogen Hexylphosphonate SCHEMBL27487198 | 0.82 | CETP (0.60) | PPARDCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988981-B2 | Thermal insulation coating composition and thermal insulation coating layer | HYUNDAI MOTOR COMPANY (KR) | 2018-06-05 | — | — | US | disclosed |
| US-9988981-B2 | Thermal insulation coating composition and thermal insulation coating layer | HYUNDAI MOTOR COMPANY (KR) | 2018-06-05 | — | — | US | disclosed |
| US-20150184588-A1 | THERMAL INSULATION COATING COMPOSITION AND THERMAL INSULATION COATING LAYER | HYUNDAI MOTOR COMPANY (KR) | 2015-07-02 | — | — | US | disclosed |
| US-20150184588-A1 | THERMAL INSULATION COATING COMPOSITION AND THERMAL INSULATION COATING LAYER | HYUNDAI MOTOR COMPANY (KR) | 2015-07-02 | — | — | US | disclosed |
| US-20090155828-A1 | METHODS OF DETECTING PROSTATE CANCER | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-06-18 | — | — | US | disclosed |
| US-20060171947-A1 | Serine/threonine hydrolase proteins and screening assays | BURNHAM INSTITUTE | 2006-08-03 | — | — | US | disclosed |
| US-7083987-B2 | Activity based probe analysis | ACTIVX BIOSCIENCES, INC. (US) | 2006-08-01 | — | — | US | disclosed |
| US-20050287594-A1 | Activity-based probes having specificity to the active form of enzymes and receptors; screening for desired biological activities or target proteins | SCRIPPS RESEARCH INSTITUTE, THE | 2005-12-29 | — | — | US | disclosed |
| US-6872574-B2 | Generating and screening compound libraries that are used for the identification of lead molecules, and for the parallel identification of their biological targets | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1364209-A4 | ACTIVITY BASED PROBE ANALYSIS | ACTIVX BIOSCIENCES INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030096328-A1 | Serine/threonine hydrolase proteins and screening assays | BURNHAM INSTITUTE | 2003-05-22 | — | — | US | disclosed |
| WO-2003023355-A2 | SERINE/THREONINE HYDROLASE PROTEINS AND SCREENING ASSAYS | THE BURNHAM INSTITUTE (US) | 2003-03-20 | — | — | WO | disclosed |
| EP-1275006-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | The Scripps Research Institute (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020182652-A1 | Proteomic analysis | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-12-05 | — | — | US | disclosed |
| WO-2002063271-A2 | ACTIVITY BASED PROBE ANALYSIS | ACTIVX BIOSCIENCES, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
| US-20020064799-A1 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE OF AN ASSIGNMENT | 2002-05-30 | — | — | US | disclosed |
| US-20020045194-A1 | Proteomic analysis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-04-18 | — | — | US | disclosed |
| US-20020040275-A1 | Proteomic analysis | THE SCRIPPS RESEARCH INSTITUTE | 2002-04-04 | — | — | US | disclosed |
| WO-2001077684-A2 | PROTEOMIC ANALYSIS USING ACTIVITY-BASED PROBE LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001077668-A2 | PROTEOMIC ANALYSIS USING ACTIVE-SITE DIRECTED PROBES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2001-10-18 | — | — | WO | disclosed |