SCHEMBL4283101

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15517564	0.89	SMN1; SMN2 (0.54)	SMN1; SMN2NPC1RAB9AHPGDPPIA
	SCHEMBL4403626	0.89	SMN1; SMN2 (0.61)	SMN1; SMN2NPC1RAB9AHPGDPPIA
	SCHEMBL4276687	0.87	SMN1; SMN2 (0.52)	SMN1; SMN2NPC1RAB9AHPGDPPIA
	SCHEMBL4279981	0.86	HSD17B10 (0.61)	SMN1; SMN2NPC1RAB9AHPGDPPIA
	SCHEMBL340393	0.85	SMN1; SMN2 (0.72)	SMN1; SMN2NPC1RAB9AHPGDMAPT
	SCHEMBL7369113	0.85	PDE4A (0.60)	SMN1; SMN2PDE4APDE4BPDE4CPDE4D
	SCHEMBL4273797	0.85	HSD17B2 (0.55)	SMN1; SMN2PDE4APDE4BPDE4CPDE4D
	SCHEMBL15516975	0.83	NPC1 (0.53)	SMN1; SMN2NPC1RAB9AHPGDPPIA
	SCHEMBL1810999	0.83	SMN1; SMN2 (0.55)	SMN1; SMN2NPC1RAB9AHPGDPPIA
	SCHEMBL17204538	0.83	SMPD1 (0.57)	SMN1; SMN2PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.