SCHEMBL4273797

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23876967	0.94	ALDH1A1 (0.59)	HSD17B2CA12CA1CA2CA7
	SCHEMBL18789684	0.88	CA12 (0.62)	HSD17B2CA12CA1CA2CA7
	SCHEMBL4283101	0.85	SMN1; SMN2 (0.53)	PDE4APDE4BPDE4CPDE4DMAPT
	SCHEMBL3470800	0.83	HSD17B2 (0.57)	HSD17B2CA12CA1CA2CA7
	SCHEMBL14705104	0.82	KMT2A (0.48)	PDE4APDE4BPDE4CPDE4DALDH1A1
	SCHEMBL28033776	0.81	KMT2A (0.56)	PDE4APDE4BPDE4CPDE4DMAPT
	SCHEMBL15417529	0.80	PDE4A (0.45)	PDE4APDE4BPDE4CPDE4DALDH1A1
	SCHEMBL29440131	0.80	PDE4A (0.45)	PDE4APDE4BPDE4CPDE4DALDH1A1
	SCHEMBL7684319	0.79	MAPT (0.77)	HSD17B2CA12CA1CA2CA7
	SCHEMBL7093941	0.79	ALDH1A1 (0.62)	HSD17B2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.