SCHEMBL428355

SCHEMBL428355

O=C(O)CCCCCNC(=O)c1ccc(C(=O)NCCCCCC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 1.00
CYP1A2 P05177 1/20 0.78
CYP2C9 P11712 1/20 0.78
CYP2C19 P33261 1/20 0.78
POLB P06746 3/20 0.66
LMNA P02545 1/20 0.65
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
HDAC6 Q9UBN7 7/20 0.63
HDAC3 O15379 6/20 0.63
HDAC4 P56524 6/20 0.63
HDAC1 Q13547 6/20 0.63
HDAC7 Q8WUI4 6/20 0.63
HDAC2 Q92769 6/20 0.63
HDAC10 Q969S8 6/20 0.63
HDAC11 Q96DB2 6/20 0.63
HDAC8 Q9BY41 6/20 0.63
HDAC9 Q9UKV0 6/20 0.63
HDAC5 Q9UQL6 6/20 0.63
KDM4E B2RXH2 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9183154 0.95 MAPK1 (0.90) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL5658185 0.93 MAPK1 (0.87) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL10659200 0.93 MAPK1 (0.86) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL10865398 0.93 MAPK1 (0.86) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL5655215 0.93 MAPK1 (0.86) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL1231651 0.93 MAPK1 (0.86) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL9717451 0.92 MAPK1 (0.85) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL23923673 0.92 MAPK1 (0.84) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL5659485 0.92 MAPK1 (0.84) MAPK1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL2631253 0.92 MAPK1 (0.84) MAPK1CYP1A2CYP2C9CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596092-B2 PARTICLES WITH A PLURALITY OF COATINGS PROCTER & GAMBLE (US) 2020-04-01 EP claimed
EP-2555742-B2 ENCAPSULATES PROCTER & GAMBLE (US) 2018-12-05 EP claimed
EP-2756065-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2018-10-24 EP claimed
EP-2596092-B1 PARTICLES WITH A PLURALITY OF COATINGS PROCTER & GAMBLE (US) 2017-05-31 EP claimed
US-9644174-B2 Encapsulates THE PROCTER & GAMBLE COMPANY (US) 2017-05-09 US claimed
EP-2555742-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2016-03-16 EP claimed
EP-2756065-A1 ENCAPSULATES The Procter and Gamble Company (US) 2014-07-23 EP claimed
EP-2596092-A1 PARTICLES WITH A PLURALITY OF COATINGS The Procter and Gamble Company (US) 2013-05-29 EP claimed
EP-2596093-A1 DELIVERY PARTICLES WITH A PLURALITY OF CORES The Procter & Gamble Company (US) 2013-05-29 EP claimed
WO-2013040114-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2013-03-21 WO claimed
US-20130061883-A1 ENCAPSULATES PROCTER & GAMBLE COMPANY, THE 2013-03-14 US claimed
EP-2555742-A1 ENCAPSULATES The Procter & Gamble Company (US) 2013-02-13 EP claimed
WO-2012012475-A1 DELIVERY PARTICLES WITH A PLURALITY OF CORES THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO claimed
WO-2012012494-A1 PARTICLES WITH A PLURALITY OF COATINGS THE PROCTER & GAMBLE COMPANY (US) 2012-01-26 WO claimed
WO-2011127030-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2011-10-13 WO claimed
WO-1995029149-A1 PROCESS FOR THE PREPARATION OF BIS(AMIDOCARBOXYLIC ACIDS) UNILEVER N.V. (NL) 1995-11-02 WO claimed
US-5410076-A Reacting an acyl halide and an aminocarboxylate compound formed from lactams and aminocarboxylic acids in a basic medium; acidification; precipitation LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-04-25 US claimed
US-5393902-A Reacting diester with lactam or salt of aminocarboxylic acid in alcohol solvent, recovering product LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-02-28 US claimed
EP-4747001-A2 SILICA CAPSULES The Procter & Gamble Company (US) 2026-05-27 EP disclosed
US-5393902-A Reacting diester with lactam or salt of aminocarboxylic acid in alcohol solvent, recovering product LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1995-02-28 US disclosed