Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428355 | 0.95 | MAPK1 (1.00) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL10363539 | 0.91 | MAPK1 (0.72) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL5658185 | 0.88 | MAPK1 (0.87) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL1231651 | 0.88 | MAPK1 (0.86) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL5655215 | 0.88 | MAPK1 (0.86) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL10865398 | 0.88 | MAPK1 (0.86) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL10659200 | 0.88 | MAPK1 (0.86) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL9717451 | 0.87 | MAPK1 (0.85) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL23923673 | 0.87 | MAPK1 (0.84) | MAPK1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL6258138 | 0.87 | MAPK1 (0.84) | MAPK1CYP1A2CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410076-A | Reacting an acyl halide and an aminocarboxylate compound formed from lactams and aminocarboxylic acids in a basic medium; acidification; precipitation | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1995-04-25 | — | — | US | disclosed |