SCHEMBL42837

SCHEMBL42837

CN(C)C(C)(C)c1ccccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
TSHR P16473 4/20 0.60
TDP1 Q9NUW8 2/20 0.60
CA2 P00918 3/20 0.39
ALOX15 P16050 4/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 2/20 0.39
HIF1A Q16665 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 2/20 0.39
NPC1 O15118 1/20 0.39
CA12 O43570 1/20 0.39
GMNN O75496 1/20 0.39
EGFR P00533 1/20 0.39
FYN P06241 1/20 0.39
POLB P06746 1/20 0.39
CA3 P07451 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758408 0.79 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL148945 0.79 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL15129713 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ALOX15
Water SCHEMBL11573406 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL4616729 0.78 ALDH1A1 (0.68) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL12566253 0.77 TSHR (0.48) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL584830 0.75 ALDH1A1 (0.71) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL9327128 0.75 ALDH1A1 (0.71) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL22729938 0.75 ALDH1A1 (1.00) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL410880 0.75 ALDH1A1 (0.71) ALDH1A1TSHRTDP1CA2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582799-A2 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL Codexis, Inc. (US) 2013-04-24 EP disclosed
WO-2011159910-A2 BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF (S)-3-(1-AMINOETHYL)-PHENOL CODEXIS, INC. (US) 2011-12-22 WO disclosed
EP-2349976-A1 A PROCESS FOR PRODUCING (S)-3-Ý(1-DIMETHYLAMINO)ETHYL¨PHENYL-N-ETHYL-N-METHYL-CARBAMATE VIA NOVEL INTERMEDIATES Jubilant Life Sciences Limited (IN) 2011-08-03 EP disclosed
WO-2010023535-A1 A PROCESS FOR PRODUCING (S)-3-[(1-DIMETHYLAMINO)ETHYL] PHENYL-N-ETHYL-N-METHYL-CARBAMATE VIA NOVEL INTERMEDIATES JUBILANT ORGANOSYS LIMITED (IN) 2010-03-04 WO disclosed