Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 7/20 | 0.39 |
| ▸ | AMY2A | P04746 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625348 | 1.00 | AMY1A (0.44) | AMY1AMEN1KMT2ASTAT3AMY2A | |
| SCHEMBL4283707 | 1.00 | AMY1A (0.44) | AMY1AMEN1KMT2ASTAT3AMY2A | |
| SCHEMBL28150659 | 1.00 | AMY1A (0.44) | AMY1AMEN1KMT2ASTAT3AMY2A | |
| SCHEMBL25223048 | 0.88 | AMY1A (0.48) | AMY1AMEN1KMT2ASTAT3AMY2A | |
| SCHEMBL11049043 | 0.88 | AMY1A (0.48) | AMY1AMEN1KMT2ASTAT3AMY2A | |
| SCHEMBL5058335 | 0.88 | MEN1 (0.49) | MEN1KMT2AMAPTL3MBTL1PTPN1 | |
| SCHEMBL4083047 | 0.88 | MEN1 (0.49) | MEN1KMT2AMAPTL3MBTL1PTPN1 | |
| SCHEMBL8893292 | 0.88 | MEN1 (0.49) | MEN1KMT2AMAPTL3MBTL1PTPN1 | |
| SCHEMBL22466775 | 0.88 | MEN1 (0.49) | MEN1KMT2AMAPTL3MBTL1PTPN1 | |
| SCHEMBL5058331 | 0.88 | MEN1 (0.49) | MEN1KMT2AMAPTL3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5660818-A | APPLYING A FLAVONOIDS CITRUS PLANT EXTRACTS FOR SUN AND CHEMICAL DAMAGE PROTECTION, STIMULATING HAIR AND NAIL GROWTH | L'OREAL (FR) | 1997-08-26 | — | — | US | claimed |
| EP-0681827-B1 | Use of bioflavonoids as protecting agent for keratin materials | OREAL (FR) | 1997-01-22 | — | — | EP | claimed |
| EP-0681827-A1 | Use of bioflavonoids as keratineous phaners protection agent | L'OREAL (FR) | 1995-11-15 | — | — | EP | claimed |
| US-7481845-B2 | Composition for protecting keratin material, process of making, uses thereof | L'OREAL (FR) | 2009-01-27 | — | — | US | disclosed |
| EP-1588705-A1 | Use of coumarin derivatives | INTE:LIGAND Software-Entwicklungs und Consulting GmbH (AT) | 2005-10-26 | — | — | EP | disclosed |
| US-20050166336-A1 | Composition for protecting keratin material, process of making, uses thereof | L'OREAL (FR) | 2005-08-04 | — | — | US | disclosed |
| US-5660818-A | APPLYING A FLAVONOIDS CITRUS PLANT EXTRACTS FOR SUN AND CHEMICAL DAMAGE PROTECTION, STIMULATING HAIR AND NAIL GROWTH | L'OREAL (FR) | 1997-08-26 | — | — | US | disclosed |
| EP-0681827-B1 | Use of bioflavonoids as protecting agent for keratin materials | OREAL (FR) | 1997-01-22 | — | — | EP | disclosed |
| EP-0681827-A1 | Use of bioflavonoids as keratineous phaners protection agent | L'OREAL (FR) | 1995-11-15 | — | — | EP | disclosed |
| US-3947405-A | Process for making neohesperidine dihydrochalcone | GIVAUDAN CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050166336-A1 | Composition for protecting keratin material, process of making, uses thereof | KRT18, CKAP4, KLK5 | AMY1A 1226/4885MEN1 3722/4885KMT2A 1937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.