Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976621 | 0.80 | POLB (0.40) | LMNAALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL3633847 | 0.76 | POLB (0.42) | POLBCYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2637224 | 0.76 | POLB (0.42) | LMNAALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL6493288 | 0.75 | POLB (0.39) | LMNAALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL5550657 | 0.73 | POLB (0.40) | ALDH1A1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6483365 | 0.72 | CYP3A4 (0.39) | ALDH1A1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2976897 | 0.71 | SMN1; SMN2 (0.50) | LMNAALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL10006209 | 0.70 | POLB (0.38) | LMNAALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL11872917 | 0.70 | LMNA (0.42) | LMNAALDH1A1LPAR3LPAR1SMN1; SMN2 | |
| SCHEMBL6496046 | 0.70 | LPAR3 (0.44) | LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077186-A1 | NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESLLSCHAFT (DE) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070909-A1 | Non-steroidal progesterone receptor modulators | Bayer Schering Pharma AG (DE) | 2009-06-17 | — | — | EP | disclosed |