Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272275 | 0.76 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1TP53TSHRALOX15 | |
| SCHEMBL2455996 | 0.75 | NR1H2 (0.51) | SMN1; SMN2ALDH1A1TP53TSHRALOX15 | |
| SCHEMBL132588 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TP53TSHRALOX15 | |
| SCHEMBL4267425 | 0.71 | NR1H2 (0.35) | — | |
| SCHEMBL15302725 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TSHRCYP3A4ESR2HPGD | |
| SCHEMBL14007770 | 0.69 | ESR2 (0.56) | SMN1; SMN2TP53ESR2NPC1RAB9A | |
| SCHEMBL11228368 | 0.69 | ALDH1A1 (0.88) | SMN1; SMN2ALDH1A1TP53TSHRALOX15 | |
| SCHEMBL19880405 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1TP53TSHRALOX15 | |
| SCHEMBL8576732 | 0.69 | ALDH1A1 (0.88) | SMN1; SMN2ALDH1A1TP53TSHRALOX15 | |
| SCHEMBL13657118 | 0.69 | ESR2 (0.50) | SMN1; SMN2TP53ESR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608673-B2 | Organosilane compound and organosilica obtain therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-10-27 | — | — | US | disclosed |
| US-7608673-B2 | Organosilane compound and organosilica obtain therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20080227941-A1 | Organosilane compound and organosilica obtained therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080227941-A1 | Organosilane compound and organosilica obtained therefrom | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227941-A1 | Organosilane compound and organosilica obtained therefrom | OR51E2, WEE1, WEE2 | SMN1; SMN2 4683/4885ALDH1A1 428/4885TP53 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.