Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665923 | 1.00 | GRM5 (0.55) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL23781631 | 0.81 | CYP2A6 (0.50) | GRM5CHRNB2HCAR2CYP2A6CHRNA4 | |
| SCHEMBL13778510 | 0.78 | CYP2A6 (0.56) | GRM5ALDH1A1CHRNB2CYP2A6CHRNA4 | |
| SCHEMBL23781611 | 0.78 | HCAR2 (0.43) | GRM5CHRNB2HCAR2ATMNPC1 | |
| SCHEMBL81832 | 0.77 | FFAR1 (0.41) | GRM5ALDH1A1MELKKCNJ5KCNJ3 | |
| SCHEMBL31044591 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL29170155 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL30750480 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL22031562 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL3722709 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1MELKCHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4685143-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | Vivozon,Inc. (KR) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024196136-A1 | DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF | 주식회사 비보존 | 2024-09-26 | — | — | WO | disclosed |
| WO-2009153536-A1 | 1-AZA-BICYCLO [2.2.2] OCTANE DERIVATIVES USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | ARGENTA DISCOVERY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009153536-A1 | 1-AZA-BICYCLO [2.2.2] OCTANE DERIVATIVES USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | ARGENTA DISCOVERY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |