Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22031562 | 1.00 | GRM5 (0.48) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL31044618 | 0.81 | GRM5 (0.35) | GRM5CHRNB2HCAR2CHRNA4NPC1 | |
| SCHEMBL17657690 | 0.81 | GRM5 (0.36) | GRM5CHRNB2HCAR2CHRNA4 | |
| SCHEMBL28412023 | 0.81 | GRM5 (0.35) | GRM5CHRNB2HCAR2CHRNA4NPC1 | |
| SCHEMBL6786135 | 0.77 | ALDH1A1 (0.38) | GRM5ALDH1A1MELKKCNJ5KCNJ3 | |
| SCHEMBL32665923 | 0.77 | GRM5 (0.55) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL30750480 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL29170155 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL4284069 | 0.77 | GRM5 (0.55) | GRM5ALDH1A1MELKCHRNB2CHRNA3 | |
| SCHEMBL3722709 | 0.77 | GRM5 (0.48) | GRM5ALDH1A1MELKCHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743457-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR THERAPEUTIC USE | 4M THERAPEUTICS INC. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015045-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR THERAPEUTIC USE | 4M THERAPEUTICS INC. (US) | 2025-01-16 | — | — | WO | disclosed |
| CN-111285873-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |