Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.63 |
| ▸ | PGR | P06401 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284983 | 0.84 | NR3C1 (0.76) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL292126 | 0.84 | NR3C1 (0.86) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634217 | 0.80 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL292521 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL292195 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL292264 | 0.77 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291520 | 0.77 | NR3C1 (0.98) | NR3C1NR3C2PGR | |
| SCHEMBL5813222 | 0.75 | NR3C1 (0.68) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1633631 | 0.74 | NR3C1 (0.63) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL291778 | 0.74 | NR3C1 (0.77) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049112-A2 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | Bausch & Lomb Incorporated (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008021728-A2 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED' GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |